This article highlights some of the best and worst matchups for wide receivers and tight ends each week. Using player tracking data from various sources (NFL.com, Pro Football Focus, ESPN, etc.) and reviews of recent trends, I look for situations to exploit or avoid when setting your weekly lineups. Given that this article is intended to help across all sites (both DFS and season-long), variations in pricing and scoring systems are not considered, so obviously, the values could shift depending on where you are playing. The main intent of this article is simply to call out some players who could be significantly helped or hurt by their situations each week.

Favorable Matchups

WR Amon-Ra St. Brown (DET vs GB) vs Javon Bullard

St. Brown is always a must-start in any format right now, but he is walking into a great matchup this week against Bullard in the slot. Green Bay has struggled against receivers outside of Jaire Alexander, with Bullard currently allowing over half a fantasy point per coverage snap and being targeted 27% of the time. St. Brown is the most trusted weapon through the air for Detroit, and should see another big game this week.

WR DeAndre Hopkins (KC vs TB) vs Tyrek Funderburk

Hopkins had another full week of practice with Kansas City and should be more familiar with the playbook and this offense. He is walking into a great spot against Funderburk on the outside, who is currently allowing 0.50 fantasy points per coverage snap while being targeted 15% of the time. He may not be targeted as much as others in the secondary, but that means he is allowing big plays all over the field. Look for Hopkins to assimilate into this offense and put up big numbers this week with a great matchup against Tampa Bay.

WR Malik Nabers (NYG vs WAS) vs Benjamin St-Juste

Nabers had a quiet return from concussion in a tough matchup against Pittsburgh. However, he should be all systems go in a great spot against St-Juste on the outside this week. St-Juste is routinely asked to cover the top receiver and has not fared well from a fantasy standpoint. He currently allows 0.46 fantasy points per coverage snap and is being targeted 23% of the time. Nabers could easily resume his double-digit target share this week and power this offense back to relevance all on his own.

WR Terry McLaurin (WAS vs NYG) vs Deonte Banks

Banks had success against McLaurin earlier this season, but that was before the breakout with Jayden Daniels. Since that week, Banks has allowed 0.42 fantasy points per coverage snap and is being targeted 21% of the time. Teams are not afraid of going after the shadow corner, and McLaurin has emerged as Daniels' favorite option this season. This is another great spot for the former Buckeye receiver and should be taken advantage of across the board.

WR Calvin Ridley (TEN vs NE) vs Christian Gonzalez

Just like Banks above, teams have not been afraid to throw at Gonzalez. The young corner came back from injury this season and has been asked to shadow top receivers to the tune of 0.35 fantasy points per coverage snap and being targeted 21% of the time. Ridley is the main beneficiary of the DeAndre Hopkins trade and saw 13 targets last week. Look for his role to continue to grow in this offense, as he is the best pass-catching option they have.

WR Ladd McConkey (LAC vs CLE) vs Greg Newsome II

Newsome is one of the better slot corners in the league from a defensive standpoint, but he has allowed fantasy points in bunches this year. He currently allows 0.45 fantasy points per coverage snap and is being targeted 22% of the time. The offense did not do the defense any favors early this season, and a lot of those numbers are based on sheer volume. McConkey has emerged as the top pass-catching option for Justin Herbert and should see his production continue this week. McConkey is easily a WR2/FLEX option this week.

TE Cade Otton (TB vs KC)

Otton has exploded onto the scene with a combined 47 fantasy points over the past 2 weeks and is quickly becoming the top option for Baker Mayfield with both Mike Evans and Chris Godwin injured. Otton has seen 20 targets over the past 2 weeks and the Kansas City defense has allowed the most fantasy points to opposing tight ends this season. Otton has a chance at another top 5 finish at the tight end position this week.

TE David Njoku (CLE vs LAC)

Njoku is a must-start in any format this week, as his stock has risen with Jameis Winston under center. Njoku has 40 fantasy points and 21 targets over the past 2 weeks. He is easily one of the top targets for Winston and was integral in the upset of the Ravens last week. The Chargers have not allowed a touchdown to an opposing tight end this season, but Travis Kelce did have 15 points against them in week 4. Look for Njoku to continue his hot streak this week.