There's a lot of NFL news to sift through. We compile all of the fantasy-relevant news and notes you'll need in a bulleted list of matchup previews.
Read along with an accompanying podcast from Dave Kluge and Jeff Bell as they dive deep into this week's biggest storylines.
Bye Weeks
Kansas City Chiefs, Minnesota Vikings, Los Angeles Rams, Miami Dolphins
Thursday Night Football
San Francisco 49ers @ Seattle Seahawks
Sunday London Game - Sunday, 9:30 am ET
Jacksonville Jaguars @ Chicago Bears
- Marcedes Lewis (rest) did not practice Thursday
- Gabe Davis (knee) limited Wednesday and Thursday
- Evan Engram (hamstring) limited Wednesday and Thursday, HC Doug Pederson is optimistic that he’ll return in Week 6
- Travis Etienne Jr. (shoulder) limited Wednesday and Thursday; avoided serious injury
- Devin Duvernay (hamstring) placed on IR
- Jaguars' travel plans pushed back due to Hurricane Milton
Sunday Early Games - Sunday, 1:00 pm ET
Washington Commanders @ Baltimore Ravens
- Brian Robinson Jr. (knee) did not practice Wednesday or Thursday
- Austin Ekeler (heel) limited Wednesday, full participant Thursday
- Noah Brown (groin) limited Wednesday and Thursday
- Rashod Bateman (groin) did not practice Wednesday, limited Thursday
- Charlie Kolar (toe) limited Wednesday, full participant Thursday
- Rasheen Ali (neck) practicing in full
Arizona Cardinals @ Green Bay Packers
- Zay Jones (hamstring) full participant Wednesday, limited Thursday, back from suspension
- Christian Watson (ankle) limited Wednesday and Thursday
- Romeo Doubs back from suspension
- Tucker Kraft (groin) full participant Wednesday, limited Thursday
- Luke Musgrave (ankle) placed on IR
Houston Texans @ New England Patriots
- Nico Collins (hamstring) placed on IR
- Joe Mixon (ankle) did not practice Wednesday, limited Thursday, told reporters he feels good, will make decision after Friday’s practice
- Dameon Pierce (hamstring) limited Wednesday, full participant Thursday, on track to play
- Robert Woods (foot) did not practice Wednesday or Thursday, not expected to play
- Rhamondre Stevenson (foot) did not practice Wednesday or Thursday
- Kendrick Bourne (knee) limited Wednesday or Thursday
- K.J. Osborne (shoulder) limited Wednesday and Thursday
- Drake Maye will start in Week 6
Tampa Bay Buccaneers @ New Orleans Saints
- Rachaad White (foot) limited Wednesday, did not practice Thursday
- Jalen McMillan (hamstring) limited Wednesday and Thursday
- Trey Palmer (concussion) did not practice Wednesday or Thursday
- Taysom Hill (rib) did not practice Wednesday or Thursday
- Alvin Kamara (hand) did not practice Wednesday, limited Thursday
- Rashid Shaheed (hip) did not practice Wednesday, limited Thursday, expects to play
- KenDre Miller (hamstring) practicing in full
- Derek Carr (oblique) did not practice Wednesday or Thursday; expected to miss multiple games
- Spencer Rattler will start in Week 6
Cleveland Browns @ Philadelphia Eagles
- Nick Chubb (knee) limited Wednesday and Thursday
- D'Onta Foreman (ankle) did not practice Wednesday, limited Thursday
- Nyheim Hines (knee) limited Wednesday and Thursday
- Pierre Strong Jr (hamstring) limited Wednesday and Thursday
- Amari Cooper (rest) did not practice Wednesday, full participant Thursday
- Jerry Jeudy (knee) practicing in full
- David Njoku (knee/ankle) did not practice Wednesday, limited Thursday
- Deshaun Watson won’t be benched, per HC Kevin Stefanski
- A.J. Brown (hamstring) practicing in full
- DeVonta Smith (concussion) practicing in full
- Johnny Wilson (concussion) practicing in full
Indianapolis Colts @ Tennessee Titans
- Josh Downs (toe) did not practice Wednesday or Thursday
- Michael Pittman Jr (back) did not practice Wednesday or Thursday, expected to miss some time, candidate for IR
- Anthony Richardson (oblique) limited Wednesday, full participant Thursday
- Jonathan Taylor (ankle) did not practice Wednesday or Thursday, says ankle is "way better"
- Trey Sermon (collarbone) did not practice Wednesday, full participant Thursday
- DeAndre Hopkins (rest) limited Wednesday, full participant Thursday
- Treylon Burks (personal) did not practice Wednesday, full participant Thursday
- Will Levis (shoulder) practicing in full
Sunday Afternoon Games - Sunday, 4:05-4:25 pm ET
Los Angeles Chargers @ Denver Broncos
- Gus Edwards (ankle) did not practice Wednesday or Thursday
- Justin Herbert (ankle) limited Wednesday and Thursday
- Hayden Hurst (Achilles) limited Wednesday, full participant Thursday
- Audric Estime (ankle) practicing in full
- Josh Reynolds (hand) did not practice Wednesday or Thursday
Pittsburgh Steelers @ Las Vegas Raiders
- Russell Wilson (calf) practicing in full, working with second team
- Najee Harris (rest) did not practice Wednesday, full participant Thursday
- Jaylen Warren (knee) limited Wednesday and Thursday
- Cordarrelle Patterson (ankle) ruled out
- Pat Freiermuth (calf) full participant Wednesday, limited Thursday
- MyCole Pruitt (knee) limited Wednesday and Thursday
- Davante Adams (hamstring) did not practice Wednesday or Thursday; trade talks cooling down
- Jakobi Meyers (ankle) did not practice Wednesday or Thursday
- Zamir White (groin) did not practice Wednesday or Thursday
- Michael Mayer (personal) did not practice Wednesday or Thursday
- Aidan O'Connell will start in Week 6
Atlanta Falcons @ Carolina Panthers
- Darnell Mooney (knee) limited Wednesday and Thursday
- Bijan Robinson (hamstring) full participant Wednesday, limited Thursday
- Diontae Johnson (ankle) limited Wednesday and Thursday
- Xavier Legette (shoulder) practicing in full
- Tommy Tremble (concussion) did not practice Wednesday or Thursday
- Ian Thomas (calf) full participant Wednesday, limited Thursday
Detroit Lions @ Dallas Cowboys
- Dante Pettis and Denzel Mims worked out for Dallas on Tuesday
Sunday Night Football - Sunday, 8:20 pm ET
Cincinnati Bengals @ New York Giants
- Chase Brown (quadricep) full participant Wednesday, limited Thursday
- Zack Moss (foot) did not practice Wednesday, limited Thursday
- Joe Burrow (right wrist) practicing in full
- Mike Gesicki (hamstring) did not practice Wednesday, limited Thursday
- Malik Nabers (concussion) did not practice Wednesday or Thursday
- Devin Singletary (groin) limited Wednesday and Thursday, trending in the right direction per HC Brian Daboll
Monday Night Football - Monday, 8:15 pm ET
Buffalo Bills @ New York Jets
- Josh Allen (left hand/ankle) practicing in full, avoids concussion protocol
- James Cook (toe) did not practice
- Darrynton Evans (hamstring) practicing in full
- Khalil Shakir (ankle) did not practice
- Mack Hollins (shoulder) limited
- Curtis Samuel (toe) limited
- Tyler Conklin (hip) limited
- Aaron Rodgers (ankle) limited
- HC Robert Saleh fired; Jeff Ulbrich named interim head coach
- OC Nathaniel Hackett relieved of play-calling duties; Todd Downing to take over
Photos provided by Imagn Images
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matchup previews
Week 6